Polycystic kidney of the real case

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Polycystic kidney diet precautions

Capsule kidney caused by renal insufficiency, uremic patients, in addition to early detection of early treatment, but also should pay attention to the following aspects:
Quit or reduce consumption

1: Alcoholic beverages:

Alcohol, especially white wine, for patients with polycystic kidney disease should quit, alcohol and polycystic kidney kidney irritation is important. It can stimulate polycystic protein activity, accelerate cyst growth.
2: fermented food:

Here the fermentation of food is mainly fermented food, such as fermented bean curd, rotten eggs. Avoid eating this will be beneficial to the growth rate of cysts.

3: high protein food:

Every kidney disease, should be low-protein diet, to avoid the body of nitrogen metabolites synthesis, reduce the excretion of the kidneys. Such as soybeans, tofu, and other beans products.
4: visceral food：

Animals made of internal organs cooked food is not suitable for patients with polycystic kidney disease, especially animal liver. In the process of slaughtering animals, many toxins remain in the liver, kidney, especially the liver, the function of the liver is detoxification, many animal metabolic toxins Are left in the internal organs, if the patient taking these substances after the invisible increase in burden on the kidneys, aggravate the condition.
5:

Coffee, chocolate is strictly prohibited

Should eat more food
1:

Contains high vitamin fruits and vegetables.
2:

Iron-rich fruits and vegetables, such as carrots and so on.
3:

Can be fossil fossil vegetable food, such as black fungus and so on
4:

A diuretic effect of food.
5:

Alkaline foods are also taken, can play a therapeutic role

Polycystic kidney disease in patients with life matters needing attention

Polycystic kidney disease belongs to a congenital hereditary disease. For patients with polycystic kidney disease, the importance of daily rehabilitation and maintenance will be better than the clinical short-term treatment. Polycystic kidney disease in patients with cyst enlargement is a multi-factor to promote the results, therefore, polycystic kidney disease patients must be more attention to these incentives to control their own condition, delay the progression of the disease. The following describes the daily routine of polycystic kidney disease major attention, hope to be helpful to everyone.

Polycystic kidney disease Note 1:
prevention of cold suffering from polycystic kidney disease kidney disease patients heart is very painful, because with other kidney disease is not the same, polycystic kidney disease is a lifelong genetic disease, accompanied by a lifetime, both Is particularly attention, the family's caring more care, still can not stop the cysts continue to enlarge the objective reality. At this point, such as suffering from colds, especially repeated cold will make the polycystic kidney disease kidney damage increased by one, play a worse effect of deterioration, but also accelerate the progress of renal injury.

Polycystic kidney Note 2: prevention of trauma

Polycystic kidney cysts continue to swollen, will lead to cysts within the pressure increased, forcing the patient's kidneys are also increasing, increased intra-abdominal pressure. Such as any slight trauma, such as sprains, bruises, falls, etc. will increase the abdominal pressure or external injury directly to the impact of swelling of the cyst, with a high internal pressure of the cyst rupture, bleeding, easy to induce infection.

Polycystic kidney Note three: control good blood pressure

The vast majority of patients with polycystic kidney disease in the kidney before the damage will appear high blood pressure, we call the polycystic kidney disease has been developed: the emergence of high blood pressure will accelerate the damage of renal function, while high blood pressure will be on the heart Vascular damage, the polycystic kidney disease associated with cerebrovascular rupture caused by stroke and other serious complications, so control of blood pressure to delay the deterioration of renal function, to prevent complications is essential.

Polycystic kidney Note 4: control a good diet

The rational treatment of patients with polycystic kidney disease is very important to control the progress of renal function deterioration. Use low-salt diet 2 to 3 grams per day consumption of salt is appropriate, eat less potassium, phosphorus, diet, low protein, low fat diet, eat more rich in vitamins and plant crude fiber diet, keep stool smooth.

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How do patients with polycystic kidney disease?

This is worthy of attention, because the occurrence of polycystic kidney disease so that patients bear a small harm, damage to everyone's body and spirit, want to avoid the occurrence of disease hazards, we need to find their own treatment, the correct treatment can Reduce the occurrence of disease hazards, then how to care for patients with polycystic kidney disease?
How to care for patients with polycystic kidney disease:

1, the patient should be pillow supine, head to the side, timely inhalation of oxygen and keep the airway patency. 6 hours after the smooth condition can be changed to semi-recumbent position, in order to facilitate retroperitoneal drainage, 24 hours after surgery can get up, the day can be into the semi-liquid food, 2 days later can be improved food.

2, polycystic kidney disease should be carefully fixed after the peritoneal drainage tube, to avoid folding, compression and plug the drainage tube, close observation of drainage fluid color, nature and quantity changes, more drainage, blood pressure often suggest that there may be bleeding , Should be dealt with in a timely manner.

3, should be closely observed in patients with respiratory rate, depth, rhythm, attention to incision and puncture hole dressing bleeding and abdominal conditions, can guide patients to take a deep breath, effective cough, promote sputum discharge, given the amount of oxygen intake.

4, more cysts, polycystic kidney or cyst protrusion is not obvious, thick wall of the patients prone to leakage, should be given adequate drainage to prevent leakage, keep the drainage tube to prevent clogging outside the urine Infiltration into the abdominal cavity infection. Drainage fluid to be significantly reduced after the drainage tube can be removed.

How to care for patients with polycystic kidney disease? The above aspects of the recommendations given by experts, hope to cause everyone's attention, of course, polycystic kidney damage serious, want to avoid the occurrence of disease hazards, we grasp the polycystic kidney disease patients how to care, But also should actively consult the recommendations of relevant experts, thereby reducing the incidence of disease hazards.
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Learn more about the process of polycystic kidney disease

Polycystic kidney a class of kidney with hereditary nephropathy, the incidence and development of a certain law, polycystic kidney staging have the following rules,

First, the occurrence period: the disease is a genetic disease, generally born
That is, cysts, but smaller, difficult to detect, 20 years old generally not easy to find, but the family if the case of polycystic kidney disease, should be early check, and early observation of the growth of cysts. Pay attention to maintenance.

Second, the growth period: the patient in the 30-40 years old, the cyst will have a faster growth, medicine, this period is called the growth period. Growth should strengthen the observation, Western medicine treatment of this period there is no way that do not need treatment, but symptomatic treatment, such as high blood pressure, which is very passive. In this period should be actively treated, the purpose of treatment is through the use of a strong blood circulation of traditional Chinese medicine, so that cysts no longer grow or delay the growth rate of cysts to achieve the role of prolonging the life of patients can also be said that this is Traditional Chinese medicine to promote blood circulation to delay the critical period of cyst growth.

Third, the swollen period: the patient into the 40 years of age, the cyst will have further growth swelling, when the cyst more than 4cm later, to the cyst collapse of this period, known as the enlargement period. With the expansion of cysts will appear more clinical symptoms, such as low back pain, proteinuria, hematuria, blood pressure, etc., then should be closely observed in the treatment, this period is a critical period of Chinese and Western combination therapy. Can be used to prevent blood circulation to eliminate renal function of cystic fluid to achieve the purpose of protecting renal function, so the polycystic kidney disease is a combination of traditional Chinese and Western medicine to protect the critical period of renal function.

Fourth, the broken period: If the cysts continue to grow, in some external factors, there will be ulceration, rupture should be immediately after hospitalization, and actively control the infection, to prevent acute exacerbation of sepsis and renal function, in order to facilitate other symptoms deal with.

5, uremia period: for uremic treatment, protection of renal function, advanced ventral hemodialysis surgery.

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The causes of polycystic kidney disease

The exact cause of this disease is unclear, about half of a family history, in adults as dominant inheritance, while the baby for the hidden genetic. Pathology of the kidney is often swollen, 2-3 times larger than normal, depending on whether the color or bleeding and other factors may be dark red, dark brown, brown and so on. Cysts may be large or small, small diameter of less than 0.1cm, large can be very large, cut the kidneys were honeycomb-like blocks, cysts can communicate with each other, but not connected with the renal pelvis, cystic compression of renal parenchyma fibrosis Changes, the capsule liquid was pale yellow or bloody, the wall by the cubic epithelial cells, the wall below the many arteries, due to increased pressure and combined infection and other reasons, or even bleeding caused by bleeding hematuria.

Polycystic kidney disease is a common hereditary nephropathy, polycystic kidney disease is mainly genetic factors. There may be three mutant genes that cause polycystic kidney disease in adults. PKD1, PKD2 and PKD3, respectively, which have been identified as PKD1 and PKD2 genes have been cloned. PKD1 is the most important cause of adult polycystic kidney disease, accounting for about 85%, and the most serious symptoms. PKD1 gene located in 16p13.3-p13.12, long 52kb, containing 46 exons, of which exon 1 to 34 for the multi-copy area, exon 35 to 46 for the single copy area, accounting for 70% And 30% of the region, the protein product consists of 4302 amino acid residues of a glycoprotein, known as polycystin-1. The content of G and C in the gene sequence was 62.5%, and exon 22 and intron 21 were enriched with a long 2.5kb and 0.5kb polypuronine-polypyrimidine sequence, which was easy to form three strands of DNA. The 1-33 exons contain the number of Alu repeats (2-11), and there are 6 homologous sequence regions in other parts of the chromosome. It is estimated that more than 80% of the pkd1 gene mutations occur in the repetitive sequence of the gene. There are few types of gene mutations in the region, most of which are concentrated in the 3 'end-specific fragment (the repeat region), and the remaining mutations may spread throughout the gene , There are missing, shift code, no sense and missense mutation. PKD2 gene located in 4q21-q23, gene length 68kb, composed of 15 exons, encoding polycystin-2 is composed of 968 amino acid residues in the membrane channel protein. PKD2 gene mutations are both germ cell and somatic. These mutations include small deletions, insertions, and single base substitutions that lead to early termination of translation, as well as missense mutations and mutations in the cleavage site.

Although most of the symptoms occurred in adults, but in the fetus began to form. Cysts originated in the renal tubules, the liquid properties with the origin of different parts, originated in the proximal tubules, cyst fluid components such as Na +, K +, CI-, H +, creatinine, urea and plasma similar to the origin; The concentration of Na +, K + in the cysts was lower, and the concentrations of CI-, H +, creatinine and urea were higher.

Abnormal proliferation of intraepithelial epithelial cells is one of the significant characteristics of ADPKD, in a mature incomplete or re-development state, highly suggestive of the development of mature regulation of bacteria obstacles, so that cells in an immature state, which shows strong proliferation Sex. The abnormality of this cell is another significant feature of ADPKD, which is manifested as the subunit combination, distribution and activity of Na + -K + -ATPase, which is closely related to cell transport, and changes in cell signaling abnormalities and ion transport channels. Abnormal proliferation of extracellular matrix is ​​the third significant feature of ADPKD. Many studies have shown that these abnormalities are involved in cell growth-related activity factors. But the key part of the unusual links and the way is not yet clear. In short, due to genetic defects caused by cell growth changes and interstitial abnormalities, one of the important pathogenesis of this disease.

Polycystic kidney is what it is harmful to.

Polycystic kidney disease is a hereditary nephropathy, accounting for end-stage renal insufficiency of the total 5% --- 10%.
Polycystic kidney disease with age, cysts gradually increased, the earliest performance is:
        Waist pain, elevated blood pressure, kidney B-type abnormalities. If not timely control, renal cysts continue to increase, oppression of the surrounding renal function unit will cause its damage, start the process of renal fibrosis, early manifestations of urine test: protein and blood cells;
If the process of renal fibrosis has not been effectively stopped, there will be increased serum creatinine or glomerular filtration rate decreased, and ultimately the development of end-stage renal failure.
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